Natera, Inc. (NTRA) Stock Analysis

Natera, Inc. (NTRA) Stock Analysis

Analysis from 10-Q filed 2025-11-07. Data as of Q4 2025.

Overall Grade: F (Concerning)

Natera, Inc. faces challenges in financial performance that warrant careful analysis.

Metric Value Context
ROIC -17.3% Below expectations
FCF Margin 4.7% Cash flow pressure
Debt/Equity 0.0x Conservative leverage

Investment Thesis: Financial metrics indicate concerning business quality with areas requiring attention.

Explore Natera, Inc.: Earnings History | Filing Intelligence | ROIC Analysis


Profitability: Natera, Inc. earns -17.3% ROIC, Bottom 50% in Healthcare

Natera, Inc.'s trailing-twelve-month ROIC of -17.3% ranks Bottom 50% in Healthcare companies (sector median: -3.9%), driven by NOPAT margin of -10.4% combined with asset turnover of 1.3x. Source: 10-Q filed 2025-11-07. Gross margin of 64.7% with operating margin at -13.4% reflects strong pricing power.

Metric NTRA Rating Context
Return on Invested Capital (ROIC) -17.3% Red flag Below sector median of -3.9%
Return on Equity (ROE) -16.0% Red flag Moderate equity returns
Gross Margin 64.7% Excellent Strong pricing power
Operating Margin -13.4% Warning Moderate operational efficiency

Cash Flow: Natera, Inc. generates $109.1M FCF at 4.7% margin, positive NaN/8 quarters

Natera, Inc. generated $109.1M in free cash flow (TTM), a 4.7% FCF margin, a margin that ranks Top 50% in Healthcare. FCF was positive in N/A of the last 8 quarters. Source: 10-Q filed 2025-11-07.

Metric NTRA Rating Context
Free Cash Flow Margin 4.7% Warning Thin cash margins
Free Cash Flow (TTM) $109.1M Good Positive cash generation
OCF/Net Income -1.0x Warning Potential accrual concerns
FCF Consistency (8Q) N/A Warning Variable cash flow

Balance Sheet: Natera, Inc. at 0.0x leverage

Natera, Inc.'s debt-to-equity ratio of 0.0x reflects conservative leverage. Net cash position of $1.0B provides financial flexibility. Source: 10-Q filed 2025-11-07.

Metric NTRA Rating Context
Debt to Equity 0.0x Excellent Conservative capital structure
Net Cash Position $1.0B Excellent Net cash positive

Valuation: Natera, Inc. trades at -150.7x earnings

Natera, Inc. trades at a P/E of -150.7x. Free cash flow yield of 0.3% reflects market expectations for growth.

Metric NTRA Rating Context
P/E Ratio -150.7x Red flag Reasonable valuation
EV/Sales 13.2x Warning Growth premium priced in
FCF Yield 0.3% Warning Lower cash yield

Capital Allocation: Natera, Inc. returns 0.0% shareholder yield

Natera, Inc.'s total shareholder yield is 0.0% (dividends + buybacks). Source: 10-Q filed 2025-11-07.

Metric NTRA Rating Context
Total Shareholder Yield 0.0% Warning Dividend + buyback yield combined
Total Capital Returned (TTM) $0 Adequate Dividends + buybacks returned to shareholders

Sector Rankings

Metric Value Percentile vs Median
Return on Invested Capital (ROIC) -17.3% Bottom 50% -
Free Cash Flow Margin 4.7% Top 50% -
Gross Margin 64.7% Top 50% 1.0x above
Operating Margin -13.4% Bottom 50% -7.0x below
Return on Equity (ROE) -16.0% Top 50% -

Financial Scorecard

Metric NTRA Rating Sector Context
Return on Invested Capital (ROIC) -17.3% Red flag Bottom 50% of sector (median: -3.9%)
Free Cash Flow Margin 4.7% Warning Top 50% of sector (median: 0.0%)
Gross Margin 64.7% Excellent Top 50% of sector (median: 64.0%)
Debt to Equity Ratio 4.7% Excellent Conservative capital structure
Free Cash Flow Yield 0.3% Red flag Growth-focused valuation

Frequently Asked Questions

Q: What is Natera, Inc.'s Return on Invested Capital (ROIC)?

Natera, Inc. (NTRA) has a trailing twelve-month Return on Invested Capital (ROIC) of -17.3%. This compares below the sector median of -3.9%. An ROIC below 8% suggests the company may be destroying shareholder value.

Q: What is Natera, Inc.'s Free Cash Flow Margin?

Natera, Inc. (NTRA) has a free cash flow margin of 4.7%, generating $109.1 million in free cash flow over the trailing twelve months. A thin FCF margin may indicate heavy reinvestment or operational challenges.

Q: Is Natera, Inc. stock overvalued or undervalued?

Natera, Inc. (NTRA) trades at a P/E ratio of -150.7x, which is above the sector median of N/A. The EV/Sales multiple is 13.2x. Free cash flow yield is 0.3%, reflecting growth expectations priced into the stock.

Q: What is Natera, Inc.'s revenue and earnings growth?

Natera, Inc. (NTRA) grew revenue by 35.9% year-over-year. Earnings per share increased by 0.7% compared to the prior year. Double-digit revenue growth indicates strong demand and market share gains.

Q: How does Natera, Inc. compare to competitors in Healthcare?

Compared to other companies in Healthcare, Natera, Inc. (NTRA) shows: ROIC of -17.3% is below the sector median of -3.9% (Bottom 37%). FCF margin of 4.7% exceeds the sector median of 0.0% (Top 30% of sector). Gross margin at 64.7% is 0.8 percentage points higher than sector peers. These rankings are based on MetricDuck's analysis of all Healthcare companies with available SEC filings.

Q: What warning signs should I watch for with Natera, Inc.?

Investors in Natera, Inc. (NTRA) should monitor these potential warning signs: 1) FCF margin is thin at 4.7%, leaving limited buffer for economic downturns. Regular monitoring of SEC filings and quarterly trends is recommended.


Data Source: Data sourced from 10-Q filed 2025-11-07. TTM metrics as of Q4 2025.

Methodology: Financial metrics calculated from SEC 10-K and 10-Q filings using standardized formulas. Sector comparisons use peer group based on SIC code.

Scope: This analysis covers SEC filing fundamentals — profitability, cash flow, balance sheet, and valuation metrics. For analyst estimates and price targets, consult sell-side research.

This analysis is for informational purposes only and does not constitute investment advice.