Natera, Inc. (NTRA) Factsheet

Natera, Inc. (NTRA) Stock Analysis

Analysis from 10-Q filed 2025-11-07. Data as of Q4 2025.

Overall Grade: F (Concerning)

Grade F (Concerning). ROIC -17.3%. FCF margin 4.7%. D/E 0.0x. Source: 10-Q filed 2025-11-07.

Metric Value Context
ROIC -17.3% Below expectations
FCF Margin 4.7% Cash flow pressure
Debt/Equity 0.0x Conservative leverage

ROIC -17.3% — Bottom 50% of sector peers. FCF margin 4.7% — Top 50%.

Explore Natera, Inc.: Earnings History | Filings | ROIC Analysis

Programmatic access: Available via MCP at mcp.metricduck.com. Tools for NTRA: get_company_overview, get_filing_index (lens: debt_stress, management_outlook, risk_trajectory), get_filing_changes, get_metric_history, compare_companies, screen_filing_signals.


Profitability: Natera, Inc. earns -17.3% ROIC, Bottom 50% in Healthcare

ROIC TTM -17.3%, sector median -2.5%, Bottom 50%. DuPont: NOPAT margin -10.4% × asset turnover 1.3x. Gross margin 64.7%. Operating margin -13.4%. Source: 10-Q filed 2025-11-07.

Metric NTRA Rating Context
Return on Invested Capital (ROIC) -17.3% Red flag Below sector median of -2.5%
Return on Equity (ROE) -16.0% Red flag Moderate equity returns
Gross Margin 64.7% Excellent Strong pricing power
Operating Margin -13.4% Warning Moderate operational efficiency

Cash Flow: Natera, Inc. generates $109.1M FCF at 4.7% margin, positive NaN/8 quarters

FCF TTM $109.1M. FCF margin 4.7%, Top 50%. OCF/Net income -1.0x. Positive FCF in NaN/8 trailing quarters. Source: 10-Q filed 2025-11-07.

Metric NTRA Rating Context
Free Cash Flow Margin 4.7% Warning Thin cash margins
Free Cash Flow (TTM) $109.1M Good Positive cash generation
OCF/Net Income -1.0x Warning Potential accrual concerns
FCF Consistency (8Q) N/A Warning Variable cash flow

Balance Sheet: Natera, Inc. at 0.0x leverage

Debt/Equity 0.0x. Net cash $1.0B. Source: 10-Q filed 2025-11-07.

Metric NTRA Rating Context
Debt to Equity 0.0x Excellent Conservative capital structure
Net Cash Position $1.0B Excellent Net cash positive

Valuation: Natera, Inc. trades at -150.7x earnings

P/E -150.7x. EV/Sales 13.2x. FCF yield 0.3%. Source: 10-Q filed 2025-11-07.

Metric NTRA Rating Context
P/E Ratio -150.7x Red flag Reasonable valuation
EV/Sales 13.2x Warning Growth premium priced in
FCF Yield 0.3% Warning Lower cash yield

Capital Allocation: Natera, Inc. returns 0.0% shareholder yield

Total shareholder yield 0.0%. Capital returned $0 TTM. Source: 10-Q filed 2025-11-07.

Metric NTRA Rating Context
Total Shareholder Yield 0.0% Warning Dividend + buyback yield combined
Total Capital Returned (TTM) $0 Adequate Dividends + buybacks returned to shareholders

Sector Rankings

Metric Value Percentile vs Median
Return on Invested Capital (ROIC) -17.3% Bottom 50% -
Free Cash Flow Margin 4.7% Top 50% -
Gross Margin 64.7% Top 50% 1.0x at
Operating Margin -13.4% Bottom 50% -5.8x below
Return on Equity (ROE) -16.0% Top 50% -

Financial Scorecard

Metric NTRA Rating Sector Context
Return on Invested Capital (ROIC) -17.3% Red flag Bottom 50% of sector (median: -2.5%)
Free Cash Flow Margin 4.7% Warning Top 50% of sector (median: 0.0%)
Gross Margin 64.7% Excellent Top 50% of sector (median: 64.7%)
Debt to Equity Ratio 4.7% Excellent Conservative capital structure
Free Cash Flow Yield 0.3% Red flag Growth-focused valuation

Frequently Asked Questions

Q: What is Natera, Inc.'s Return on Invested Capital (ROIC)?

Natera, Inc. (NTRA) has a trailing twelve-month Return on Invested Capital (ROIC) of -17.3%. Sector median -2.5%. Source: 10-Q filed 2025-11-07.

Q: What is Natera, Inc.'s Free Cash Flow Margin?

Natera, Inc. (NTRA) has a free cash flow margin of 4.7%, generating $109.1 million in free cash flow over the trailing twelve months. Source: 10-Q filed 2025-11-07.

Q: What is Natera, Inc.'s P/E ratio and how does it compare to peers?

Natera, Inc. (NTRA) trades at a P/E ratio of -150.7x, which is above the sector median of N/A. EV/Sales 13.2x. FCF yield 0.3%. Source: 10-Q filed 2025-11-07.

Q: What is Natera, Inc.'s revenue and earnings growth?

Natera, Inc. (NTRA) grew revenue by 35.9% year-over-year. EPS +0.7% YoY. Source: 10-Q filed 2025-11-07.

Q: How does Natera, Inc. compare to competitors in Healthcare?

Compared to other companies in Healthcare, Natera, Inc. (NTRA) shows: ROIC -17.3%, sector median -2.5% (Bottom 50%). FCF margin 4.7%, sector median 0.0% (Top 50%). Gross margin 64.7%, 0.0pp below sector median. These rankings are based on MetricDuck's analysis of all Healthcare companies with available SEC filings.

Q: What warning signs should I watch for with Natera, Inc.?

Quantitative warning flags for Natera, Inc. (NTRA): 1) FCF margin 4.7% (below 5%). Source: 10-Q filed 2025-11-07.


Data Source: Data sourced from 10-Q filed 2025-11-07. TTM metrics as of Q4 2025.

Methodology: Financial metrics calculated from SEC 10-K and 10-Q filings using standardized formulas. Sector comparisons use peer group based on SIC code.

Scope: This analysis covers SEC filing fundamentals — profitability, cash flow, balance sheet, and valuation metrics. For analyst estimates and price targets, consult sell-side research.

This analysis is for informational purposes only and does not constitute investment advice.