Immunocore Holdings plc (IMCR) Earnings History

Immunocore Holdings plc - Q4 FY2025 Earnings

Filed at: Feb 25, 2026, 7:30 AM EST|Read from source

EXECUTIVE SUMMARY

Immunocore reported strong revenue growth driven by KIMMTRAK sales, demonstrating commercial momentum. The company is advancing its clinical pipeline with anticipated data readouts in oncology and plans to initiate its first autoimmune candidate trial, supported by a solid cash position.

POSITIVE HIGHLIGHTS

  • •

    KIMMTRAK net product sales increased 24% year-over-year to $104.5 million in Q4 2025 and 29% year-over-year to $400.0 million for FY 2025.

    positive
  • •

    Demonstrated commercial momentum with 15 consecutive quarters of KIMMTRAK revenue growth.

    positive
  • •

    Cash, cash equivalents and marketable securities increased to $864.2 million as of December 31, 2025, up from $820.4 million in the prior year.

    positive
  • •

    Net loss improved to $30.1 million in Q4 2025 from $23.8 million in Q4 2024, and full year net loss improved to $35.5 million from $51.1 million in 2024.

    positive

CONCERNS & RISKS

  • •

    Operating loss widened in Q4 2025 to $19.7 million from $19.5 million in Q4 2024, and full year operating loss was $45.4 million compared to $70.5 million in 2024, indicating continued unprofitability.

    attention
  • •

    R&D expenses increased significantly to $78.8 million in Q4 2025 from $60.9 million in Q4 2024, and full year R&D expenses rose to $274.9 million from $222.2 million, driven by preclinical and clinical expenses for autoimmune programs and Phase 3 trials.

    attention
  • •

    SG&A expenses increased slightly to $42.6 million in Q4 2025 from $42.3 million in Q4 2024, and full year SG&A expenses rose to $165.4 million from $155.8 million, due to costs supporting a growing pipeline and global commercial expansion.

    attention
  • •

    Net cash used in operating activities was $10.7 million in FY 2025, a significant decrease from $26.1 million provided by operating activities in FY 2024.

    negative
  • •

    Guidance for 2026 anticipates moderating revenue growth, suggesting a slowdown from the current growth trajectory.

    attention

FINANCIAL METRICS

Revenue
Quarterly
$104.48M
+24.3%
Prior year: $84.05M
Annual (YTD)
$400.02M
N/A
Prior year: $309.99M
Net Income
Quarterly
$-30.06M
-26.5%
Prior year: $-23.77M
Annual (YTD)
$-35.51M
N/A
Prior year: $-51.09M
EPS (Diluted)
Quarterly
$-0.60
-27.7%
Prior year: $-0.47
Operating Income
Quarterly
$-19.69M
-1.2%
Prior year: $-19.45M
Annual (YTD)
$-45.35M
N/A
Prior year: $-70.46M
EPS (Basic)
Quarterly
N/A
N/A

MARGIN ANALYSIS

Operating Margin
Current Quarter
-18.9%
Prior Year
-23.1%
YoY Change
+429 bps
Net Margin
Current Quarter
-28.8%
Prior Year
-28.3%
YoY Change
-47 bps

Margin expansion indicates improving profitability and operational efficiency. Measured in basis points (bps): 100 bps = 1.0%.

MANAGEMENT GUIDANCE

FY2026

revenue
"expect moderating revenue growth"

Forward-looking guidance is subject to change and does not constitute a guarantee. Actual results may differ materially from these estimates.

MANAGEMENT COMMENTARY

With $400 million in KIMMTRAK sales and a diverse clinical portfolio, Immunocore had a productive year of growth and progress in 2025.

— Immunocore Holdings plc, Q4 FY2025 2025 Earnings Call

Our priority for 2026 is the clear execution of our clinical trials, particularly as we anticipate key data in oncology and begin our first trial in autoimmune disease.

— Immunocore Holdings plc, Q4 FY2025 2025 Earnings Call

We remain focused on the long-term goal of developing medicines that can significantly improve patient lives.

— Immunocore Holdings plc, Q4 FY2025 2025 Earnings Call

Commentary excerpts from earnings call transcripts provide management's perspective on performance, strategy, and outlook. Always review full transcripts for complete context.

OPERATIONAL METRICS

Europe sales growth
N/A
+79.0% YoY
percent
KIMMTRAK net product sales
104.5M
+24.3% YoY
Prior year: 84.1M
dollars
US sales growth
N/A
+13.0% YoY
percent

Operational metrics provide insight into business drivers and customer engagement beyond traditional financial measures.