Dashboard|GH – Overview

Guardant Health, Inc.

Healthcare • CIK: 0001576280

Market Cap

$6.44B

P/E (TTM)

-15.5x

Rev Growth (TTM)

—

Net Margin (TTM)

-49.9%

FCF Yield (TTM)

—

FCF Margin (TTM)

-32.8%

LATEST EARNINGS

•

Q4 2025

•

15 days ago

•View source

Revenue

$281.27M

+39.0%

Net Income

$-128.49M

-15.8%

EPS

$-1.00

-11.1%

Gross

65.0%↑ +3.0%

Operating

-43.0%↑ +19.4%

Net

-45.7%↑ +9.3%

•Total revenue increased 39% year-over-year to $281.3 million in Q4 2025.
•Oncology revenue grew 30% to $189.9 million, with test volume up 38% year-over-year.
•Screening revenue saw substantial growth, reaching $35.1 million with approximately 38,000 Shield screening tests in Q4 2025, up from 6,400 in the prior year.
•Non-GAAP gross margin improved to 66% in Q4 2025 from 63% in Q4 2024.

View Full Earnings →

Cash Flow Health

Free Cash Flow0/8 positive

TTM$-272M

Q2 '25

$-66M+2%

Q1 '25

$-67M+19%

FCF Margin

TTM-32.8%

Q2 '25-28.4%+14%

Sector: 0.0%Below Avg

OCF Margin–

OCF/NI0.58x

CapEx Coverage7.2x

FCF Yield–

FCF Growth (2Y)–

Cash Conversion Cycle

–

View Insights from Latest Filing →View Full Cash Flow Statement →

Capital Allocation & Returns

Total Shareholder Yield

TTM0.0%

Div Yield0.0%

Insufficient data

Dividend & Payout Metrics

Dividend Yield (TTM)0.0%

Free Cash Flow (TTM)$-271.7M

Est. Dividends Paid (TTM)$0

Shows how management rewards shareholders

Operational Efficiency & Returns

Return on Invested CapitalTTM

43.6%

P25MedianP75

75th pctl (med: 0.0%)

DuPont BreakdownROIC = Margin × Turn × (1+D/E)

NOPAT Margin

-55.7%

Asset Turnover

0.57x

Leverage (1+D/E)

1.00x

D/E: 0.00x

DuPont: -31.6% ≈ 43.6% ROIC

Asset & CapEx Efficiency

Invested Cap Turn

-0.78x

8Q:–

CapEx Intensity

-3.1%

8Q:–

Asset-based ROIC formula

Full Analysis

QUARTERLY TRENDS

Last 8 quarters + TTM

Metric	TTM	Q2 2025	Q1 2025	Q4 2024	Q3 2024	Q2 2024	Q1 2024	Q4 2023	Q3 2023
Revenue	$828.8M	$232.1M↑14.1%	$203.5M↑0.8%	$201.8M↑5.4%	$191.5M↑8.0%	$177.2M↑5.2%	$168.5M↑8.7%	$155.1M↑8.4%	$143.0M
Operating Income	$-460.7M	$-106.4M↑4.2%	$-111.0M↑11.8%	$-126.0M↓7.4%	$-117.3M↓16.6%	$-100.6M↓0.9%	$-99.7M↑49.5%	$-197.5M↓74.0%	$-113.5M
Net Income	$-413.8M	$-99.9M↓5.0%	$-95.2M↑14.3%	$-111.0M↓3.0%	$-107.8M↓5.0%	$-102.6M↑10.7%	$-115.0M↑38.5%	$-187.0M↓117.2%	$-86.1M
Operating Cash Flow	$-238.5M	$-60.3M↑3.8%	$-62.7M↑2.8%	$-64.5M↓26.3%	$-51.1M↑45.7%	$-94.0M↓210.4%	$-30.3M↑61.5%	$-78.7M↓1.2%	$-77.8M
Free Cash Flow	$-271.7M	$-65.9M↑1.8%	$-67.1M↑19.5%	$-83.4M↓50.9%	$-55.3M↑44.2%	$-99.1M↓166.2%	$-37.2M↑55.1%	$-82.8M↓3.3%	$-80.2M
Total Equity	N/A

Income Statement Cash Flow Statement Balance Sheet

Valuation Analysis

Fair Value

Price-to-EarningsTTM

-15.5x

Valuation Lenses

Earnings

-15.5x

vs – sector

Cash Flow

-12.2x

EV/FCF vs –

Growth-Adj

–PEG

N/A

Quality-Adj

–P/E per %ROIC

ROIC: 43.6%

Shareholder Returns

Dividend

–

Buyback

–

Total Yield

–

Market Cap$6.44B

EV–

Multi-angle valuation analysis with sector context

Business Quality & Moat

Overall Quality Score

82/100

Exceptional

Composite score: Returns (40%) + Consistency (30%) + Earnings Quality (30%)

Returns on Capital

Return on Equity (ROE)Top 10%

2.7%

8Q:–

Return on Invested Capital (ROIC)Top 25%

43.6%

8Q:–

DuPont Analysis (ROIC = NOPAT Margin × Asset Turnover)

NOPAT Margin: -55.7%

Asset Turnover: 0.57x

Earnings Quality

Cash Conversion

0.58x

OCF / Net Income

FCF Consistency

–

Positive quarters

Competitive Moat Indicators

Pricing Power

Gross Margin100.0%

Capital Efficiency

Invested Capital Turnover-0.78x

Working Capital

Cash Conversion Cycle–

Growth Quality & Momentum

Growth Rates

Revenue Growth YoY

N/A

OpInc Growth YoY

-5.8%

EPS Growth YoY

N/A

FCF 3Y CAGR

N/A

Margin Quality & Sustainability

Moderate

Profitability Cascade

Gross

100.0%

Operating

-55.6%

Top 25% in sector

Net

-49.9%

Margins Unknown

Earnings Quality Signals

SBC / Revenue

—

FCF vs Net Gap

+17.1 pts

FCF: -32.8% | Net: -49.9%

Quality = stability + cash conversion + low dilution

Balance Sheet & Solvency

Fortress

Net Debt / EBITDA

Net Cash

(0.0x)Net Cash: $735.48M

Interest Coverage

–

+Net cash position: $735.48M

Leverage Metrics

Debt-to-Equity

0.00x

Balance sheet risk & solvency analysis