|GLUE Overview
GLUE

Monte Rosa Therapeutics, Inc.

Healthcare • CIK: 0001826457

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Market Cap
$609.09M
P/E (TTM)
29.1x
Rev Growth (TTM)
+1112.3%
Net Margin (TTM)
11.5%
FCF Yield (TTM)
23.8%
FCF Margin (TTM)
79.9%

LATEST EARNINGS

Q3 2025
4 months ago
View source
Revenue
$12.77M
+38.5%
Net Income
$-27.08M
-13.5%
EPS
  • Announced a second collaboration with Novartis to develop novel degraders for immune-mediated diseases, receiving an upfront payment of $120 million and eligibility for up to $5.7 billion in total deal value.
  • Phase 1 study of NEK7-directed MGD MRT-8102 is underway, with initial data readout including high-CVD risk cohort on track for H1 2026.
  • VAV1-directed MGD MRT-6160 is advancing toward anticipated initiation of multiple Phase 2 studies in immune-mediated diseases.
  • Phase 1/2 study of GSPT1-directed MGD MRT-2359 is advancing in mCRPC patients, with additional results expected by year-end.

Cash Flow Health

Free Cash Flow3/8 positive
TTM$145M
Q3 '25
$100M+374%
Q2 '25
$-36M+23%
FCF Margin
TTM79.9%
Q3 '25781.5%+598%
Sector: 0.0%Top 10%
OCF Margin82.2%
OCF/NI7.12x
CapEx Coverage36.2x
FCF Yield23.8%
FCF Growth (2Y)
Cash Conversion Cycle
0 days
DSO: 0+DIO: DPO:

Capital Allocation & Returns

Total Shareholder Yield
TTM0.0%
Div Yield0.0%

Insufficient data

Dividend & Payout Metrics
Dividend Yield (TTM)0.0%
Free Cash Flow (TTM)$145.0M
Capital Return / FCF0.0%
Est. Dividends Paid (TTM)$0
Shows how management rewards shareholders

Operational Efficiency & Returns

Return on Invested CapitalTTM
2.6%
Volatile
+61.9%
P25MedianP75
75th pctl (med: 0.0%)
DuPont BreakdownROIC = Margin × Turn × (1+D/E)
NOPAT Margin
4.5%
Asset Turnover
0.46x
8Q: 0.12x
Leverage (1+D/E)
1.00x
D/E: 0.00x
DuPont: 2.1%2.6% ROIC
Asset & CapEx Efficiency
Fixed Asset Turn
6.19x
8Q:1.47x
+564.1%
Invested Cap Turn
0.58x
8Q:0.14x
+52.3%
CapEx Intensity
1.3%
8Q:2.1%
CapEx/Depreciation
0.50x
Asset-based ROIC formula

QUARTERLY TRENDS

Last 8 quarters + TTM

MetricTTMQ3 2025Q2 2025Q1 2025Q4 2024Q3 2024Q2 2024Q1 2024Q4 2023
Revenue
$181.5M
$12.8M45.0%
$23.2M72.7%
$84.9M40.0%
$60.6M558.1%
$9.2M96.3%
$4.7M341.3%
$1.1M
$0
Operating Income
$8.5M
$-33.0M112.0%
$-15.6M135.3%
$44.0M238.6%
$13.0M149.0%
$-26.5M18.7%
$-32.6M6.6%
$-34.9M0.2%
$-34.9M
Net Income
$20.9M
$-27.1M120.3%
$-12.3M126.2%
$46.9M248.9%
$13.4M156.3%
$-23.9M21.3%
$-30.3M5.2%
$-32.0M3.9%
$-33.3M
Operating Cash Flow
$149.1M
$100.4M389.3%
$-34.7M23.7%
$-45.5M135.3%
$128.9M714.1%
$-21.0M24.4%
$-27.8M27.2%
$-38.2M228.8%
$29.6M
Free Cash Flow
$145.0M
$99.8M374.0%
$-36.4M22.7%
$-47.1M136.6%
$128.7M701.8%
$-21.4M28.2%
$-29.8M24.7%
$-39.5M241.5%
$27.9M
Total Equity
N/A

Valuation Analysis

Fair Value
Price-to-EarningsTTM
29.1x
Volatile
8Q: -12.6x-828%
Valuation Lenses
Earnings
29.1x
vs sector
Cash Flow
2.7x
EV/FCF vs
Growth-Adj
0.0xPEG
Undervalued for growth
Quality-Adj
11.2P/E per %ROIC
ROIC: 2.6%
Shareholder Returns
Dividend
Buyback
Total Yield
Market Cap$609.09M
EV$393.09M
Multi-angle valuation analysis with sector context

Business Quality & Moat

Overall Quality Score
41/100
Average

Composite score: Returns (40%) + Consistency (30%) + Earnings Quality (30%)

Returns on Capital

Return on Equity (ROE)Above Avg
8.4%
8Q:
Return on Invested Capital (ROIC)Top 25%
2.6%
8Q:
+61.9%

DuPont Analysis (ROIC = NOPAT Margin × Asset Turnover)

NOPAT Margin: 4.5%
Asset Turnover: 0.46x

Earnings Quality

Cash Conversion

7.12x

OCF / Net Income

FCF Consistency

Positive quarters

Competitive Moat Indicators

Pricing Power

Gross Margin

Capital Efficiency

Invested Capital Turnover0.58x

Working Capital

Cash Conversion Cycle0 days

Growth Quality & Momentum

Moderate Growth
Growth Quality Score
70/100
Growth 40%
Margins 30%
FCF 20%
Consistency 10%

Growth Rates

Revenue Growth YoY
1112.3%
OpInc Growth YoY
-24.3%
EPS Growth YoY
N/A
FCF 3Y CAGR
N/A

Margin Quality & Sustainability

Low Quality
Profitability Cascade
Gross
Operating
4.7%
Above Avg in sector
Net
11.5%
Margins Unknown
Earnings Quality Signals
SBC / Revenue
FCF vs Net Gap
+68.3 pts
FCF: 79.9% | Net: 11.5%

Quality = stability + cash conversion + low dilution

Balance Sheet & Solvency

Fortress
Net Debt / EBITDA
Net Cash
(0.0x)Net Cash: $391.30M
Interest Coverage
+Net cash position: $391.30M
Leverage Metrics
Debt-to-Equity
0.00x
Balance sheet risk & solvency analysis