INSMED Inc (INSM) Stock Analysis

INSMED Inc (INSM) Stock Analysis

Overall Grade: F (Concerning)

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INSMED Inc faces challenges in financial performance that warrant careful analysis.

Key Metrics:

Metric Value Context
ROIC -71.5% Below expectations
FCF Margin -159.6% Cash flow pressure
Debt/Equity 0.7x Moderate leverage

Investment Thesis: Financial metrics indicate concerning business quality with areas requiring attention.


What is INSMED Inc's Profitability and ROIC?

INSMED Inc's return on invested capital of -71.5% is below the typical cost of capital. Gross margin of 79.7% with operating margin at -205.6% reflects the company's strong market position.

Key Metrics

Metric Value Rating Interpretation
Return on Invested Capital (ROIC) -71.5% Red flag Below cost of capital
Return on Equity (ROE) -182.0% Red flag Moderate equity returns
Gross Margin 79.7% Excellent Strong pricing power
Operating Margin -205.6% Warning Moderate operational efficiency

How Strong is INSMED Inc's Cash Flow Quality?

INSMED Inc generated $-967.6M in free cash flow over the trailing twelve months, representing a -159.6% margin. FCF was positive in N/A of the last 8 quarters, indicating variable cash generation.

Key Metrics

Metric Value Rating Interpretation
Free Cash Flow Margin -159.6% Red flag Thin cash margins
Free Cash Flow (TTM) $-967.6M Red flag Cash burn
OCF/Net Income 0.7x Adequate Potential accrual concerns
FCF Consistency (8Q) N/A Warning Variable cash flow

What is INSMED Inc's Financial Health?

INSMED Inc maintains a net cash position of $889.1M, providing significant financial flexibility.

Key Metrics

Metric Value Rating Interpretation
Debt to Equity 0.7x Adequate Moderate leverage
Net Cash Position $889.1M Excellent Net cash positive

Is INSMED Inc Stock Overvalued or Undervalued?

INSMED Inc trades at a P/E of -27.2x, representing a premium to the sector median of N/A. Free cash flow yield of -2.8% reflects market expectations for growth.

Key Metrics

Metric Value Rating Interpretation
P/E Ratio -27.2x Red flag Reasonable valuation
EV/Sales 55.8x Warning Growth premium priced in
FCF Yield -2.8% Warning Lower cash yield

Sector Rankings

Metric Value Percentile vs Median
Return on Invested Capital (ROIC) -71.5% Top 50% -
Free Cash Flow Margin -159.6% Bottom 10% -
Gross Margin 79.7% Top 50% 1.3x above
Operating Margin -205.6% Top 5% -45.7x below
Return on Equity (ROE) -182.0% Top 10% -

Rating Thresholds

Return on Invested Capital (ROIC)

Measures how efficiently a company uses its debt and equity capital to generate profits. ROIC above 15% typically indicates a competitive moat.

Rating Range Interpretation
Excellent > 20% Exceptional capital efficiency, strong competitive moat
Good 12% - 20% Above-average returns, sustainable competitive position
Adequate 8% - 12% Around cost of capital, moderate competitive position
Warning 4% - 8% Below cost of capital, value may be eroding
Red flag < 4% Significant capital destruction, fundamental issues

Current: -71.5% (Red flag - Top 50% of sector (median: 0.0%))

Free Cash Flow Margin

The percentage of revenue converted to free cash flow. Higher margins indicate stronger cash generation and business quality.

Rating Range Interpretation
Excellent > 20% Strong cash generation, high-quality business
Good 10% - 20% Healthy cash conversion
Adequate 5% - 10% Moderate cash generation
Warning 0% - 5% Thin cash margins, capital intensive
Red flag < 0% Cash burn, potential liquidity concerns

Current: -159.6% (Red flag)

Gross Margin

Revenue minus cost of goods sold as a percentage. Higher gross margins indicate pricing power and competitive advantage.

Rating Range Interpretation
Excellent > 50% Strong pricing power and competitive moat
Good 30% - 50% Healthy margins, differentiated product
Adequate 20% - 30% Moderate margins, competitive industry
Warning 10% - 20% Thin margins, commodity-like business
Red flag < 10% Very thin margins, structural challenges

Current: 79.7% (Excellent - Top 50% of sector (median: 61.4%))

Debt to Equity Ratio

Total debt divided by shareholders' equity. Lower ratios indicate more conservative financing and reduced financial risk.

Rating Range Interpretation
Excellent < 0.3x Conservative leverage, strong balance sheet
Good 0.3x - 0.7x Moderate leverage, healthy financial position
Adequate 0.7x - 1.5x Elevated leverage, monitor closely
Warning 1.5x - 3.0x High leverage, increased financial risk
Red flag > 3.0x Excessive leverage, potential distress risk

Current: 73.2% (Adequate)

Free Cash Flow Yield

Free cash flow per share divided by stock price. Higher FCF yield indicates better cash return relative to valuation.

Rating Range Interpretation
Excellent > 8% High cash return, potential value opportunity
Good 5% - 8% Solid cash yield
Adequate 3% - 5% Moderate cash return
Warning 1% - 3% Low cash yield, growth expectations
Red flag < 1% Minimal cash return to shareholders

Current: -2.8% (Red flag)


Frequently Asked Questions

Q: What is INSMED Inc's Return on Invested Capital (ROIC)?

INSMED Inc (INSM) has a trailing twelve-month Return on Invested Capital (ROIC) of -71.5%. This compares below the sector median of 0.0%. An ROIC below 8% suggests the company may be destroying shareholder value.

Q: What is INSMED Inc's Free Cash Flow Margin?

INSMED Inc (INSM) has a free cash flow margin of -159.6%, generating $-967.6 million in free cash flow over the trailing twelve months. Negative free cash flow means the company is consuming cash, which may require financing.

Q: Is INSMED Inc stock overvalued or undervalued?

INSMED Inc (INSM) trades at a P/E ratio of -27.2x, which is above the sector median of N/A. The EV/Sales multiple is 55.8x.

Q: How much debt does INSMED Inc have?

INSMED Inc (INSM) has a debt-to-equity ratio of 0.7x with total debt of $541.0 million. Despite carrying debt, the company maintains a net cash position of $889.1 million.

Q: What is INSMED Inc's revenue and earnings growth?

INSMED Inc (INSM) grew revenue by 66.7% year-over-year. Earnings per share decreased by 14.9% compared to the prior year. Double-digit revenue growth indicates strong demand and market share gains.

Q: How does INSMED Inc compare to competitors in Healthcare?

Compared to other companies in Healthcare, INSMED Inc (INSM) shows: ROIC of -71.5% is below the sector median of 0.0% (Top 26%). FCF margin of -159.6% trails the sector median of 0.0%. Gross margin at 79.7% is 18.4 percentage points higher than sector peers. These rankings are based on MetricDuck's analysis of all Healthcare companies with available SEC filings.

Q: What warning signs should I watch for with INSMED Inc?

Investors in INSMED Inc (INSM) should monitor these potential warning signs: 1) FCF margin is thin at -159.6%, leaving limited buffer for economic downturns. Regular monitoring of SEC filings and quarterly trends is recommended.


Data Source: Data sourced from 10-Q filed 2025-10-30. TTM metrics as of Q4 2025.

Methodology: Financial metrics calculated from SEC 10-K and 10-Q filings using standardized formulas. Sector comparisons use peer group based on SIC code.

This analysis is for informational purposes only and does not constitute investment advice.